Palm oil naturally contains the complete vitamin E tocotrienol spectrum: alpha, beta, gamma and delta. Each isomer is functionally unique. KLK Oleo pharmacologist Yap Wei Nay evaluated clinical outcomes of palm-derived tocotrienol supplementation related to healthy aging. 

“Tocotrienols are potent antioxidants,” she writes, adding, “Having the complete spectrum present means that you could potentially maximize the health benefits that tocotrienols have to offer.” 

Nay describes the health benefits of palm-derived tocotrienols, as supported by outcomes of published human clinical trials: 

  • Maintain healthier skin: “A clinical study on 20 subjects has shown that topical application of tocotrienols can protect skin from UV-induced erythema by up to 26% and pigmentation by up to 32%.”
  • Support heart health: Palm-derived tocotrienols have been shown in studies to help maintain cholesterol levels within normal ranges, and appear to have specific benefits regarding triglyceride levels. 
  • Support brain health.  “A clinical study on 121 subjects showed that tocotrienol supplementation could slow the progression of white matter lesions.” White matter lesions are abnormal regions in the brain that are often found in elderly people, and are associated with atherosclerosis in the small blood vessels of the brain. 
  • Support liver health. “A clinical study of 87 patients with Non-Alcoholic Fatty Liver Disease (NAFLD) showed that NAFLD became negative in 50% of patients after a year of tocotrienol supplementation twice daily, compared to only 23% in the placebo group.” 

Based on the research, Nay suggests starting to consume palm-derived tocotrienols in early adulthood, noting that because tocotrienols are fat-soluble, which typically translates to low bioavailability, it is best to take self-emulsifying formulas.